Bible Prophecy / Second Coming / A Great Persecution, or Tribulation Sign#2 A Great Persecution, or Tribulation Key Text "For then shall be great tribulation, such as was not since the beginning of the world." Matthew 24:21   Prophecy: "For then shall be great tribulation, such as was not since the beginning of the world." Matthew 24:21. "...they shall lay their hands on you, and persecute you, delivering you up to the synagogues, and into prisons, being brought before kings and rulers for my name's sake... And ye shall be betrayed both by parents, and brethren, and kinsfolks, and friends; and some of you shall they cause to be put to death." Luke 21:12,16 This prophecy points primarily to the long period of tribulation that took place during the Dark Ages and was instigated by the apostate church. It lasted more than 1,000 years, multitudes were tortured, burned at the stake, or both. Over 50 million Christians were slain for their faith in this terrible tribulation period. One writer says the apostate church "has shed more innocent blood than any other institution that has ever existed among mankind." W.E.H. Lecky, History of the Rise and Influence of the Spirit of Rationalism in Europe, (Reprint; New York: Braziller, 1955) Vol. 2, pp. 40-45. "From the birth of popery to the present time, it is estimated by careful and credible historians, that more than fifty millions of the human family, have been slaughtered for the crime of heresy by popish persecutors..." John Dowling, The History of Romanism, pp. 541-542 Back For more Bible questions and answers on a variety of topics please begin our free Bible Prophecy studies today!